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- W2389336855 abstract "Objective:To investigate the relationship between 308 bp polymorphism in tumor necrosis factor α(TNFα) gene and +252 bp in lymphotoxin α(LTα)gene and the pathogenesis of non Hodgkin′s lymphoma(NHL).Methods:The single base change polymorphism in TNFα gene and LTα gene were analyzed among 96 chinese patients with NHL and 72 normal controls by using PCR restrictive fragment length polymorphism(RFLP).Results:No difference of genotype or gene frequencies of TNFα was noted in patients and normal controls( P 0.05),whereas LTα(5.5)gene frequencies increased (NHL patients 57.81 %,healthy people 46.52 %, P = 0.04).Conclusion:TNFα gene polymorphism has no effect on NHL, but LTα(5.5)allelic type may be related to the susceptibility of Chinese Han population to some extent." @default.
- W2389336855 created "2016-06-24" @default.
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- W2389336855 date "2002-01-01" @default.
- W2389336855 modified "2023-09-25" @default.
- W2389336855 title "STUDY ON THE RELATIONSHIP BETWEEN TUMOR NECROSIS FACTOR GENETIC POLYMORPHISM AND THE PATHOGENESIS OF NON-HODGKIN′S LYMPHOMA" @default.
- W2389336855 hasPublicationYear "2002" @default.
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