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- W2389345786 abstract "Objective:To evaluate the significance of the mRNA expression of p16 and E-cad gene in the endometrial carcinoma.Methods:RT-PCR method was used to detect the mRNA expression of p16 and E-cad in 30 specimens of endometrial carcinoma and 8 normal endometrium tissue.Results:①The positive expression of p16 mRNA was significantly lower in endometrial carcinoma specimens than that in normal endometrium tissue(P0.01),but it’s not related with the pathological grade of endometrial carcinoma.②The mRNA expression of E-cad was lower in endometrial carcinoma but strongly positive in normal endometrium tissue(P0.01),and there was a negative correlation between the expression of E-cad mRNA and the pathological grade(P0.05).Conclusions:The mRNA expression of p16 and E-cad genes play an important role in the pathogenesis of the endometrial carcinoma." @default.
- W2389345786 created "2016-06-24" @default.
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- W2389345786 date "2003-01-01" @default.
- W2389345786 modified "2023-09-25" @default.
- W2389345786 title "The mRNA Expression of p16 and E-cad Gene in Endometrial Carcinoma" @default.
- W2389345786 hasPublicationYear "2003" @default.
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