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- W2389346088 abstract "Objective To study the relationship of HBV liver cirrhosis with hepatic osteodystrophy and osteoporosis.Methods From March 2008 to March 2009,bone mineral density of the patients with HBV liver cirrhosis(n=43) and that of the control group(n=21) were measured by dual-energy X-ray absorptiometry.All the women in the study were premenopausal.Serum calcium,serum phosphorus,parathyroid hormone(PTH),calcitonin(CT),interleukin-6(IL-6)levels were measured.Results The incidence rate of osteoporosis was significantly higher in the cirrhosis group than that in control group(P=0.003).Compared with control group,total femur neck T-score [(-0.860±0.705) g/cm2 vs(0.125±0.715) g/cm2,P0.001),total ulnoradial T-score [(-0.702±0.666) g/cm2 vs(0.279±0.709) g/cm2,P0.001),blood serum calcium level [(2.151±0.168) mmol/L vs(2.336±0.170) mmol/L,P0.001) were significantly lower in the cirrhosis group,serum phosphorus level [(1.051±0.077) mmol/L vs(0.961±0.069) mmol/L,P0.001),PTH level [(412.674±22.779) ng/L vs(386.000±30.223) ng/L,P0.001),CT level [(45.358±3.900) pg/L vs(30.667±3.120) pg/L,P0.001),IL-6 level [(41.795±14.988) pg/mL vs(4.077±1.555) pg/mL P0.001) were significantly higher in the cirrhosis group.The serum levels of IL-6 had a negative correlation with femur neck T-score in the cirrhosis group.Conclusion Hepatic osteodystrophy is an important complication encountered in patients with HBV liver cirrhosis,the osteoporosis is an common display of hepatic osteodystrophy,and all patients should be monitored for hepatic osteodystrophy." @default.
- W2389346088 created "2016-06-24" @default.
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- W2389346088 date "2011-01-01" @default.
- W2389346088 modified "2023-09-25" @default.
- W2389346088 title "Clinical study of hepatic osteodystrophy in patients with HBV liver cirrhosis" @default.
- W2389346088 hasPublicationYear "2011" @default.
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