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- W2389359654 abstract "Objective To investigate the value of multiplex fluorescence in situ hybridization(M-FISH) in the detection of complex chromosomal abnormalities(CCAs) of chronic lymphocytic leukemia(CLL).Methods M-FISH was used to study 6 cases of CLL with CCAs identified by conventional cytogenetics(CC).Results M-FISH found only 1 case with CCA clone,but didn′t find abnormal clones in other 3 cases.10 balanced and 9 unbalanced translocations were detected in CLL,of which der(14)t(16;14;9) had never been reported.Conclusion For CLL patients,M-FISH can find or correct the missing or misidentified chromosomal abnormalities CC failed to discover.Single-cell abnormalities were frequent in CLL." @default.
- W2389359654 created "2016-06-24" @default.
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- W2389359654 date "2006-01-01" @default.
- W2389359654 modified "2023-09-22" @default.
- W2389359654 title "DETECTING COMPLEX CHROMOSOMAL ABERRATIONS OF CHRONIC LYMPHOCYTIC LEUKEMIA WITH MULTIPLEX FLUORESCENCE IN SITU HYBRIDIZATION" @default.
- W2389359654 hasPublicationYear "2006" @default.
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