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- W2389397049 abstract "Objective To study the dynamic effects of Chinese compound medicine YILIUYIN on the macrophage infiltration and the expressions of TNF-α and iNOS in transplanted S180 tumor of mouse and to reveal the anti-tumor immune mechanism of YILIUYIN in vivo. Methods Balb/c mice were inoculated with S180 tumor cells subcutaneously in the right axilla,and 24 hours later,the mice were divided into YILIUYIN group and control group,which were orally and daily administrated with YILIUYIN and the equal volume of cold boiled-water,respectively. The mice were sacrificed and the tumors were acquired at day 10,day 20,day 30,and day 40,respectively. The macrophage infiltration and the expressions of TNF-α and iNOS were detected by immunohistochemistry staining of tumor sections. Results The macrophage infiltration of YILIUYIN group was significantly higher than that of control group at all the four time-points; the expressions of TNF-α and iNOS of YILIUYIN group had no differences with control group at time-point of day 10,but was higher than that of control group at time-points of day 20,day 30,and day 40. Conclusion The anti-tumor effects of YILIUYIN in vivo might correlate with up-regulating of the macrophage infiltration and the expressions of TNF-α and iNOS in tumor tissue." @default.
- W2389397049 created "2016-06-24" @default.
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- W2389397049 date "2008-01-01" @default.
- W2389397049 modified "2023-09-28" @default.
- W2389397049 title "Chinese medicine compound YILIUYIN enhances the macrophage infiltration and the expression of TNF-α and iNOS in transplanted S180 tumor of mouse" @default.
- W2389397049 hasPublicationYear "2008" @default.
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