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- W2389417967 abstract "Objective To provide the experimental basis for further studying effects of human papillomavirus type 16 (HPV16)or HPV18 on the oncogenic mechanisms,the location of Daxx and PML in the cervical cancer cells,such as Caski cells and HeLa cells,was analyzed.Methods Indirect immunofluorescence assay was used to analyze the subcellular location of PML and Daxx in HeLa and Caski cells under confocal microscopy.It was also used to analyze the colocalization of Daxx and HPV16 E6 protein in Caski cells.Results The green signals of Daxx and the red signals of PML were dispersed uniform in the nuclei and cytoplasm of HeLa cells or Caski cells.There was not the yellow signal when the green signals of Daxx and the red signals of PML were merged.The distribution of HPV16 E6 and Daxx was not uniform in Caski cells,but regional aggregation.The yellow signals were shown when the red signals of HPV16 E6 merged with the green signals of Daxx.Conclusions There is not any colocalization of Daxx which diffused in the nuclei and cytoplasm and PML which concentrated in PML-NBs of cytoplasm of Caski cells or HeLa cells.There are colocalizations of Daxx and HPV16 E6 protein in the nuclei and cytoplasm of Caski cells." @default.
- W2389417967 created "2016-06-24" @default.
- W2389417967 creator A5016950696 @default.
- W2389417967 date "2012-01-01" @default.
- W2389417967 modified "2023-09-26" @default.
- W2389417967 title "Location of PML and Daxx in Caski Cells and HeLa Cells" @default.
- W2389417967 hasPublicationYear "2012" @default.
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