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- W2389457851 abstract "Objective To explore significance and effect of apoptosis in forming mechanism of cleft palate induced by dexamethasone (DEX). Methods In order to get cleft palate mouse embryo model, a series of doses from 10 to 50 mg/kg DEX were injected intraperitoneally into Kunming mice at 12th gestation day (GD). The cranio maxillary sections of samples were labeled by HRP avidin biotin dUTP in situ end labeling (ISEL) and were observed morphologically and quantitatively under light microscope and electron microscope. Results The ISEL positive cells were found in treatment groups. The means of sums and cleft palate incidence have positive correlation with the doses of DEX(r=0 9911/0 9978). Conclusions There is a relationship between increasing level of apoptosis and development of cleft palates induced by DEX." @default.
- W2389457851 created "2016-06-24" @default.
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- W2389457851 date "2000-01-01" @default.
- W2389457851 modified "2023-09-25" @default.
- W2389457851 title "Experimental Study On Relationship Between Apoptosis and Cleft Palate" @default.
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