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- W2389471466 abstract "Objective To investigate the efficacy and safety of different doses of sufentanyl in continuous intravenous postoperative analgesia in a prospective,double-blind,randomized,controlled trials compared with morphine in pediatric patients underwent abdominal surgery. Methods After abdominal surgery,90 patients given continuous intravenous analgesia were divided into 3 groups: SF1 group(a bolus dose of sufentanyl 0.04 μg/kg and continuous intravenous infusion of sufentanyl 0.032 μg·kg-1·h-1),SF2 group(a bolus dose of sufentanyl 0.05 μg/kg and continuous intravenous infusion of sufentanyl 0.04 μg·kg-1·h-1),and M group(a bolus dose of morphine 40 μg/kg and continuous intravenous infusion of morphine 8 μg·kg-1·h-1).All drugs were added with droperidol with the continuous intravenous infusion of 0.03 μg·kg-1·h-1,and the lockout time was 10 minutes.Pain level(FLACC Behavioral Pain Assessment Tool 0-10),O2 saturation and adverse effects were evaluated at 1,2,4,8,12,24 and 48 h after surgery. Results There was no significant difference among the 3 groups in sex,age,weight and the sorts of surgery(P0.05).There was no significant difference in O2 saturation(P0.05) among the 3 groups.The analgesic efficacy didn't have statistical difference among the 3 groups(P0.05).There was less adverse reactions in SF1 group and SF2 group compared with M group(P0.05),and there was no statistical difference in adverse reactions between SF1 and SF2 groups. Conclusions The study shows that continuous intravenous analgesia with sufentanyl provides superior analgesia and higher patient satisfaction than morphine in children.A bolus dose of sufentanyl 0.04 μg/kg and continuous intravenous infusion of sufentanyl 0.032 μg·kg-1·h-1 may be appropriate in children." @default.
- W2389471466 created "2016-06-24" @default.
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- W2389471466 date "2009-01-01" @default.
- W2389471466 modified "2023-09-24" @default.
- W2389471466 title "The efficacy and safety of different doses of sufentanyl for continuous intravenous analgesia in children after abdominal surgery" @default.
- W2389471466 hasPublicationYear "2009" @default.
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