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- W2389559369 abstract "AIM To prepare Ginkgo biloba extract temperature-sensitive nasal in situ gel with poloxamer 407,poloxamer 188,bioadhesive polymer-Chitonsan as the matrices and evaluate in vitro release of its characteristics.METHODS Membrane-less dissolution model,bovine mucosal and sheep mucosal release method,and bag filter method were applied to the drug release characteristics of gel.RESULTS Ginkgo biloba extract temperature-sensitive nasal in situ gel was released mainly by diffusion rather than by erosion,and drug release of Ginkgo biloba extract temperature-sensitive nasal in situ gel was in line with the first-order drug release equation.CONCLUSIONThe preparation of Ginkgo biloba extract temperature-sensitive nasal in situ gel has good transdermal delivery and the characteristics of sustained release." @default.
- W2389559369 created "2016-06-24" @default.
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- W2389559369 date "2013-01-01" @default.
- W2389559369 modified "2023-09-26" @default.
- W2389559369 title "In vitro release of Ginkgo biloba extract temperature-sensitive nasal in situ gel" @default.
- W2389559369 hasPublicationYear "2013" @default.
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