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- W2389560849 abstract "Objective To evaluate the clinical efficacy of Xuesaitong Injection combined with Argatroban Injection in the treatment of progressive cerebral infarction.Methods The patients(80 cases) diagnosed as progressive cerebral infarction in People's Hospital of Tanghe County in Nanyang City from December 2010 to December 2012 were randomly divided into treatment(40 cases) and control(40 cases) groups.The patients were given dehydrant according to the increased intracranial pressure,and were given protective agent for brain cells,and were given the blood pressure controlling and hypoglycemic treatment according to the level of blood pressure and blood glucose.Based on the general treatment,patients in the control group were iv administered with Xuesaitong Injection(0.4 g) which was diluted with 5% glucose injection or physiological saline(250 mL),once daily.In addition,the patients in the treatment group were treated with Argatroban Injection(60 mg diluted with 500 mL physiological saline) through 24 h continuous iv pump infusion on the first 2 d.The next 5 d they were treated with Argatroban Injection(10 mg diluted with 100 mL physiological saline),through continuous 3 h iv infusion twice daily in the morning and evening,other was the same as the control group.The patients in the two groups were treated for 14 d.The changes of neurological function and activities of daily living were observed in the two groups before and after treatment.Results Within14 d after the treatment,the neural function defect scores of the patients in the two groups were significantly lower than those before the treatment(P0.05),and the difference between the two groups was statistically significant(P0.05).The activities of daily living capacity score after the treatment in the two groups were significantly higher than those before the treatment(P0.05),and the difference between the two groups was statistically significant(P0.05).The efficiencies for the patients both in the treatment and control groups were 95.0% and 77.5% with the significant difference(P0.05).There was no adverse drug reaction in the two groups.Conclusion Xuesaitong Injection combined with Argatroban Injection could significantly improve the neurological function and activities of daily living capacity in the patients with progressive cerebral infarction and the curative effect is significant." @default.
- W2389560849 created "2016-06-24" @default.
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- W2389560849 date "2013-01-01" @default.
- W2389560849 modified "2023-09-25" @default.
- W2389560849 title "Clinical observation of Xuesaitong Injection combined with Argatroban Injection in treatment of progressive cerebral infarction" @default.
- W2389560849 hasPublicationYear "2013" @default.
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