Matches in SemOpenAlex for { <https://semopenalex.org/work/W2389582009> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2389582009 abstract "AIM: To study the effect of Qingre Xiaozheng drink (QRXZD) on tumor growth and its mechanism. METHODS:Molecular docking serves as a method to simulate the interactions of Chinese medicine small molecules and TNF-α, Bcl-xl and CDK2 receptors by ligand-fit module of the software package Cerius2 4.10 made by Accelrys company, and we may predict QRXZD on anti-tumor mechanism. RESULTS: Fifteen molecules were shown to be better interactions with Bcl-xl than an original ligand, and thirty molecules were observed to be better interactions with TNF-α than an original ligand. The number of molecule interacting with CDK2 was twenty three. Its mechanism could be direct toxicity for tumor cells to induce apoptosis; Simultaneously the mechanism might interfere the activity of CDK2 to stop tumor cell going ahead from G1 period to S period. CONCLUSION: Molecular docking method is simple, speedy and strong scientificness, which can be used to study the mechanism of the Chinese medicine." @default.
- W2389582009 created "2016-06-24" @default.
- W2389582009 creator A5058814917 @default.
- W2389582009 date "2007-01-01" @default.
- W2389582009 modified "2023-09-24" @default.
- W2389582009 title "Study on antitumor mechanism of Qingre Xiaozheng drink by molecular docking method" @default.
- W2389582009 hasPublicationYear "2007" @default.
- W2389582009 type Work @default.
- W2389582009 sameAs 2389582009 @default.
- W2389582009 citedByCount "1" @default.
- W2389582009 countsByYear W23895820092012 @default.
- W2389582009 crossrefType "journal-article" @default.
- W2389582009 hasAuthorship W2389582009A5058814917 @default.
- W2389582009 hasConcept C116569031 @default.
- W2389582009 hasConcept C121332964 @default.
- W2389582009 hasConcept C12554922 @default.
- W2389582009 hasConcept C159110408 @default.
- W2389582009 hasConcept C170493617 @default.
- W2389582009 hasConcept C178790620 @default.
- W2389582009 hasConcept C185592680 @default.
- W2389582009 hasConcept C190283241 @default.
- W2389582009 hasConcept C32909587 @default.
- W2389582009 hasConcept C41685203 @default.
- W2389582009 hasConcept C55493867 @default.
- W2389582009 hasConcept C62520636 @default.
- W2389582009 hasConcept C71240020 @default.
- W2389582009 hasConcept C71924100 @default.
- W2389582009 hasConcept C86803240 @default.
- W2389582009 hasConcept C89611455 @default.
- W2389582009 hasConcept C98274493 @default.
- W2389582009 hasConceptScore W2389582009C116569031 @default.
- W2389582009 hasConceptScore W2389582009C121332964 @default.
- W2389582009 hasConceptScore W2389582009C12554922 @default.
- W2389582009 hasConceptScore W2389582009C159110408 @default.
- W2389582009 hasConceptScore W2389582009C170493617 @default.
- W2389582009 hasConceptScore W2389582009C178790620 @default.
- W2389582009 hasConceptScore W2389582009C185592680 @default.
- W2389582009 hasConceptScore W2389582009C190283241 @default.
- W2389582009 hasConceptScore W2389582009C32909587 @default.
- W2389582009 hasConceptScore W2389582009C41685203 @default.
- W2389582009 hasConceptScore W2389582009C55493867 @default.
- W2389582009 hasConceptScore W2389582009C62520636 @default.
- W2389582009 hasConceptScore W2389582009C71240020 @default.
- W2389582009 hasConceptScore W2389582009C71924100 @default.
- W2389582009 hasConceptScore W2389582009C86803240 @default.
- W2389582009 hasConceptScore W2389582009C89611455 @default.
- W2389582009 hasConceptScore W2389582009C98274493 @default.
- W2389582009 hasLocation W23895820091 @default.
- W2389582009 hasOpenAccess W2389582009 @default.
- W2389582009 hasPrimaryLocation W23895820091 @default.
- W2389582009 hasRelatedWork W2018493249 @default.
- W2389582009 hasRelatedWork W2104270517 @default.
- W2389582009 hasRelatedWork W2182709359 @default.
- W2389582009 hasRelatedWork W2350959956 @default.
- W2389582009 hasRelatedWork W2366848239 @default.
- W2389582009 hasRelatedWork W2615296846 @default.
- W2389582009 hasRelatedWork W2732420420 @default.
- W2389582009 hasRelatedWork W2773291967 @default.
- W2389582009 hasRelatedWork W2922271311 @default.
- W2389582009 hasRelatedWork W2930242636 @default.
- W2389582009 hasRelatedWork W2955598095 @default.
- W2389582009 hasRelatedWork W2963571866 @default.
- W2389582009 hasRelatedWork W2964766467 @default.
- W2389582009 hasRelatedWork W2969773537 @default.
- W2389582009 hasRelatedWork W2994677258 @default.
- W2389582009 hasRelatedWork W3035236982 @default.
- W2389582009 hasRelatedWork W3159758138 @default.
- W2389582009 hasRelatedWork W3185653381 @default.
- W2389582009 hasRelatedWork W3194429762 @default.
- W2389582009 hasRelatedWork W2897600589 @default.
- W2389582009 isParatext "false" @default.
- W2389582009 isRetracted "false" @default.
- W2389582009 magId "2389582009" @default.
- W2389582009 workType "article" @default.