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- W2389638523 abstract "Objective To investigate the relationship of the distribution of tumor-associated macrophages(TAM) and the prognosis of patients with gastric adenocarcinoma.Methods The expression of TAM in eighty-six gastric cancer tissues were detected by the immunohistochemical method,the relationship between the distribution of TAM and the postoperative prognosis was analyzed.Results A large number of TAM invasion were discovered in gastric adenocarcinoma tissues and cancer stroma,and the expression of TAM in cancer stroma was higher than that in cancer nest(P0.01).The expression of TAM in stage I+II cancer nest was higher than that in stage Ⅲ+Ⅳ cancer nest(P0.05),but the expression of TAM in stage Ⅰ+Ⅱ cancer stroma was lower than that in Ⅲ+Ⅳ cancer stroma(P0.01),and the ratio of cancer nest TAM/cancer stroma TAM of stage I+1I was higher than that of stage Ⅲ+Ⅳ(P0.05).Compared with the patients with low expression of TAM in cancer nest,the relapse rate was lower,and the five year survival rate was higher in patients with higher expression of TAM in cancer nest(P0.05).Compared with the patients with low expression of TAM in cancer stroma,the relapse rate was higher,and the five year survival rate was lower in patients with higher expression of TAM in cancer stroma(P0.05).With the increasing of the ratio of cancer nest TAM/cancer stroma TAM,the relapse rate degraded,the five year survival rate upgraded(P0.05).Conclusion TAM in cancer nest,TAM in cancer stroma and their ratio can be used to estimate the prognosis of patients with gastric adenocarcinoma." @default.
- W2389638523 created "2016-06-24" @default.
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- W2389638523 date "2012-01-01" @default.
- W2389638523 modified "2023-09-23" @default.
- W2389638523 title "Relationship of the distribution of tumor-associated macrophages and the prognosis of patients with gastric adenocarcinoma" @default.
- W2389638523 hasPublicationYear "2012" @default.
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