Matches in SemOpenAlex for { <https://semopenalex.org/work/W2389654158> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2389654158 endingPage "2724" @default.
- W2389654158 startingPage "2721" @default.
- W2389654158 abstract "OBJECTIVE To elucidate the genetic characteristics of clinical isolated Escherichia coli carrying plasmid-mediated quinolone resistance(PMQR) determinant gene aac(6′)-Ⅰb-cr.METHODS A total of 579 strains of E.coli were collected from 8 tertiary care hospitals;41 strains with aac(6′)-Ⅰb-cr were screened out by PCR and 41 strains of positive isolates were analyzed for other PMQR genes including qnr and qepA,mutation among quinolone resistance determining region(QRDR),pathogenic genes and common β-lactamases by PCR and sequencing;molecular typing was performed by pulsed field gel electrophoresis(PFGE).RESULTS Among 41 strains of aac(6′)-Ⅰb-cr positive E.coli isolates,the susceptibility rates to nalidixic acid,ciprofloxacin and levofloxacin reached 2.4%,2.4% and 4.8%,respectively;the rates to third generation cephalosporins were less than 33.0% and to amikacin with 88.1%.From 41 strains 68.3%(28/41) of isolates produced ESBLs,43.9%(18/41) and 46.3%(19/41) of isolates were identified belonging to clonal groups A and D while only 9.8%(4/41) of isolates belonged to clonal group B;38 isolates contained 3 or 4 points mutation on at least GyrA and ParC of QRDRs,and 1 point mutation on GyrA was detected in only three strains;significant molecular diversity was exhibited by PFGE pattern.CONCLUSION aac(6′)-Ⅰb-cr Exists in diverse genotypes of E.coli and the most isolates exhibit multi-drug resistant phenotype." @default.
- W2389654158 created "2016-06-24" @default.
- W2389654158 creator A5016157482 @default.
- W2389654158 creator A5019387835 @default.
- W2389654158 creator A5019415889 @default.
- W2389654158 creator A5040176576 @default.
- W2389654158 creator A5046310961 @default.
- W2389654158 creator A5067985339 @default.
- W2389654158 date "2010-01-01" @default.
- W2389654158 modified "2023-09-26" @default.
- W2389654158 title "Genetic characteristics of Escherichia coli carrying plasmid-mediated quinolone resistance determinant gene aac-(6′)-I b-cr." @default.
- W2389654158 hasPublicationYear "2010" @default.
- W2389654158 type Work @default.
- W2389654158 sameAs 2389654158 @default.
- W2389654158 citedByCount "0" @default.
- W2389654158 crossrefType "journal-article" @default.
- W2389654158 hasAuthorship W2389654158A5016157482 @default.
- W2389654158 hasAuthorship W2389654158A5019387835 @default.
- W2389654158 hasAuthorship W2389654158A5019415889 @default.
- W2389654158 hasAuthorship W2389654158A5040176576 @default.
- W2389654158 hasAuthorship W2389654158A5046310961 @default.
- W2389654158 hasAuthorship W2389654158A5067985339 @default.
- W2389654158 hasConcept C104317684 @default.
- W2389654158 hasConcept C135763542 @default.
- W2389654158 hasConcept C22744801 @default.
- W2389654158 hasConcept C2775876089 @default.
- W2389654158 hasConcept C2778512257 @default.
- W2389654158 hasConcept C2779922871 @default.
- W2389654158 hasConcept C42084846 @default.
- W2389654158 hasConcept C501593827 @default.
- W2389654158 hasConcept C54355233 @default.
- W2389654158 hasConcept C547475151 @default.
- W2389654158 hasConcept C86803240 @default.
- W2389654158 hasConcept C89423630 @default.
- W2389654158 hasConceptScore W2389654158C104317684 @default.
- W2389654158 hasConceptScore W2389654158C135763542 @default.
- W2389654158 hasConceptScore W2389654158C22744801 @default.
- W2389654158 hasConceptScore W2389654158C2775876089 @default.
- W2389654158 hasConceptScore W2389654158C2778512257 @default.
- W2389654158 hasConceptScore W2389654158C2779922871 @default.
- W2389654158 hasConceptScore W2389654158C42084846 @default.
- W2389654158 hasConceptScore W2389654158C501593827 @default.
- W2389654158 hasConceptScore W2389654158C54355233 @default.
- W2389654158 hasConceptScore W2389654158C547475151 @default.
- W2389654158 hasConceptScore W2389654158C86803240 @default.
- W2389654158 hasConceptScore W2389654158C89423630 @default.
- W2389654158 hasIssue "18" @default.
- W2389654158 hasLocation W23896541581 @default.
- W2389654158 hasOpenAccess W2389654158 @default.
- W2389654158 hasPrimaryLocation W23896541581 @default.
- W2389654158 hasRelatedWork W1255214968 @default.
- W2389654158 hasRelatedWork W2002393384 @default.
- W2389654158 hasRelatedWork W2030396943 @default.
- W2389654158 hasRelatedWork W2069460975 @default.
- W2389654158 hasRelatedWork W2071280230 @default.
- W2389654158 hasRelatedWork W2072971577 @default.
- W2389654158 hasRelatedWork W2107670953 @default.
- W2389654158 hasRelatedWork W2111490779 @default.
- W2389654158 hasRelatedWork W2113395677 @default.
- W2389654158 hasRelatedWork W2142428061 @default.
- W2389654158 hasRelatedWork W2148890593 @default.
- W2389654158 hasRelatedWork W2178986356 @default.
- W2389654158 hasRelatedWork W2189285131 @default.
- W2389654158 hasRelatedWork W2360458613 @default.
- W2389654158 hasRelatedWork W2378696560 @default.
- W2389654158 hasRelatedWork W2444540953 @default.
- W2389654158 hasRelatedWork W2569705918 @default.
- W2389654158 hasRelatedWork W2604387572 @default.
- W2389654158 hasRelatedWork W2735930165 @default.
- W2389654158 hasRelatedWork W2886738852 @default.
- W2389654158 hasVolume "20" @default.
- W2389654158 isParatext "false" @default.
- W2389654158 isRetracted "false" @default.
- W2389654158 magId "2389654158" @default.
- W2389654158 workType "article" @default.