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- W2389654410 abstract "Objective To evaluate the relationship between E-cadherin and epidermal tumors.Methods We investigated the expression of E-cadherin in 129 cases of human epidermal tumors including basal cell carcinoma(BCC),squamous cell carcinoma(SCC),Bowen disease,actinic keratosis(AK),keratoacanthoma(KA),and seborrhoeic keratosis(SK).By immunohistochemical staining using a monoclonal antibody specific for E-cadherin.Results Similar to the E-cadherin expressed in normal epidermis,E-cadherin was strongly expressed in cell of samples BCC,SK,and KA,whereas marked decrease or lose of E-cadherin expression was found in the cells of SCC.Compared with the normal epidermal cells the expression of E-cadherin in AK and Bowen disease was normal or reduced,with complete absence of staining in dysplasis arease.Conclusion Considering the clinical and histological features of these tumors,the reduction of E-cadherin expression is considered to be associated with the invasion and metastasis of human epidermal tumors." @default.
- W2389654410 created "2016-06-24" @default.
- W2389654410 creator A5062084611 @default.
- W2389654410 date "2004-01-01" @default.
- W2389654410 modified "2023-09-23" @default.
- W2389654410 title "The Expression of E-Cadherin in Different Epidermal Tumors" @default.
- W2389654410 hasPublicationYear "2004" @default.
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