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- W2389662904 abstract "Objective:To investigate the expression of Toll-like receptor5(TLR5) in peripheral blood mononuclear cells(PBMCs )in the patients with coronary arteriosclerosis disease(CAD ),and to explore the relationship between TLR5 expression and coronary arteriosclerosis.Methods:TLR5 mRNA levels were respectively measured by reverse transcription-polymerase chain reaction(RT-PCR) in 50 CAD patients and 40 healthy controls.And the levels of plasma lipids were determined by automatic biochemistry analyzer.Results:The mean TLR5 mRNA numbers in CAD group were significantly higher than in healthy controls 0.793±0.284 vs 0.211±0.319(P 0.01),but no significant difference was found between CAD patients with normal and abnormal levels of plasma lipids.Conclusion:The expression is increased in the patients with coronary arteriosclerosis disease.TLR5 and TLR5-mediated natural immune responses are correlated with the development and progression of arteriosclerosis." @default.
- W2389662904 created "2016-06-24" @default.
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- W2389662904 date "2010-01-01" @default.
- W2389662904 modified "2023-09-28" @default.
- W2389662904 title "Increased expression of Toll-like receptor 5 in peripheral blood mononuclear cells in patients with coronary arteriosclerosis disease" @default.
- W2389662904 hasPublicationYear "2010" @default.
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