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- W2389681631 abstract "This study was designed to evaluate the clinical effectiveness and safety of cefoxitin compared with cefmetazole in treatment of respiratory, urinary tracl aerobic infeclions and oral cavity anaerobic infections. 62 patients received cefoxitin 2g intravenously twice daily for 7-14 days,25 cases with respiratory tract aerobic infections, 27 cases with urinary tract aerobic infections and 10cases with oral cavity anaerobic infections; Other 62 patients received cefmetazole 2 g intravenously twice daily for 7 - 14 days as control, 27 cases with respiratory tract aerobic infections, 25 cases with urinary tract aerobic infections and 10 cases with oral cavity anaerobic infections. The results showed that the clinical efficacy rate, bacterial efficacy raie and bacterial clerance rate of cefoxitin to 62 patients were 90.3%,92. 7% and 92.4% respectively, with no significnt difference to cefmetazole (87. 1%,90. 4% and 91.5% respectively). 125 strains were isolated in this study. cefoxitin showed susceptible to 98.9% of aerobes, and 85.3% of anaerobes, with no significant ,difference to cefmetazole, but superior to cefozolin, gentamicin and ampicillin, and 89.6% strains had a MIC lower than 16nig/L to cefoxitin in 125 strains. Slight adverse effects occured in 7. 9% patients receiving cefoxitin, while 9. 5% of control group." @default.
- W2389681631 created "2016-06-24" @default.
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- W2389681631 date "1996-01-01" @default.
- W2389681631 modified "2023-09-25" @default.
- W2389681631 title "A RANDOMIZED CONTROLLED CLINICAL EVALUATION ON CEFOXITIN COMPARED WITH CEFMETAZOLE IN TREATMENT OF 124 PATIENTS WITH BACTERIAL INFECTIONS" @default.
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