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- W2389694346 abstract "Bacteriophage T4is a virus with well-known genetics,structure and biology.Many molecular techniques could be applied for its further modification.Site-specific mutagenesis could be used in investigating the functions of some essential T4proteins.The phage-display method,which is commonly applied in bacteriophage modifications,was successfully used to display antigens on T4's capsid platform.The phage-display system as well as site-specific mutagenesis may also be used to modify interactions between phage particles and mammalian cells or to obtain phages infecting species other than the host bacteria.These may be used in the constantly developing bacteriophage therapy.All manipulations of the bacteriophage may enable the development of vaccine technology,phage therapy,and other branches of biological and medical science.This paper mainly focused on the structure of T4protein,phage-display technique and the related phage therapy." @default.
- W2389694346 created "2016-06-24" @default.
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- W2389694346 date "2012-01-01" @default.
- W2389694346 modified "2023-09-28" @default.
- W2389694346 title "Molecular Modification of T4 Bacteriophage Proteins and Its Potential Application" @default.
- W2389694346 hasPublicationYear "2012" @default.
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