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- W2389707579 abstract "The inhibitory effects of dry matter of culture broth(DMCB) from Phellinus igniarius submerged fermentation and its fractions were evaluated with the mice transplanted Hepatoma 22 in vivo. The results showed that both of DMCB and its fractions exhibited anticancer effect and increased the life span. The potency of DMCB and its fraction II(polysaccharides) seems to be better than that of the other two fractions. The inhibitory rate at the high dose of DMCB(1,000mg/kg/d) and fraction II(360mg/kg/d) was 33.5% and 40.3% respectively. The histopathological results showed that necrosis in H22 cells was induced in both DMCB and fraction II treatment groups, and immunohistochemical detectionindicated the decrease in Bcl-2 expression and the increase in Bax expression in the cancerous tissue of the mice. DMCB from Phellinus igniarius submerged fermentation and its polysaccharides fraction possess potent antitumor activity in vivo." @default.
- W2389707579 created "2016-06-24" @default.
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- W2389707579 date "2013-01-01" @default.
- W2389707579 modified "2023-09-23" @default.
- W2389707579 title "Effects of dry matter of culture broth from Phellinus igniarius submerged fermentation and its fractions on mice hepatoma 22" @default.
- W2389707579 hasPublicationYear "2013" @default.
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