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- W2389724478 abstract "Objective To study tissues distribution of oleanolic acid nanoliposomes in rats. Methods Rats were injected with oleanolic acid nanoliposomes and solution via the tail respectively. The plasma and tissues concentrations of oleanolic acid were determined by HPLC. The targeted indicators,including r e,T e,TEC,RTEC,were used to evaluate tissue distribution. Results The AUC of oleanolic acid nanoliposomes in liver was significantly higher than solution,and r e was 2. 11,T e increased from 0. 67 to 1. 81,TECincreased from 16. 04 to 33. 23,RTECwas107. 17. Conclusion Oleanolic acid nanoliposomes can concentrated in liver and show significant liver targeting." @default.
- W2389724478 created "2016-06-24" @default.
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- W2389724478 date "2014-01-01" @default.
- W2389724478 modified "2023-09-25" @default.
- W2389724478 title "Tissue distribution of oleanolic acid nanoliposomes in rats" @default.
- W2389724478 hasPublicationYear "2014" @default.
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