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- W2389733515 abstract "Objective To investigate the expressions of cyclooxygenase-2(COX-2) and vascular endothelial growth factor-C(VEGF-C) in human colon carcinoma and their correlations with lymph node metastasis.Methods Immunohistochemical Envision-2 method was adopted in detecting COX-2 and VEGF-C protein expressions in 60 cases of colon carcinoma and 10 cases of colon adenoma as controls.Results The positive rate of COX-2 and VEGF-C expressions in colon carcinoma were significantly higher than those in the control group( 0.05).COX-2 and VEGF-C were conspicuously higher in lymph-node-positive cases than in lymph-node-negative ones( 0.05).COX-2 expression was positively associated with VEGF-C(=0.331, 0.05).Conclusions Overexpressions of COX-2 and VEGF-C play an important role in the progress and metastasis of colon carcinoma,which may also help to predict the prognosis of the carcinoma." @default.
- W2389733515 created "2016-06-24" @default.
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- W2389733515 date "2012-01-01" @default.
- W2389733515 modified "2023-09-24" @default.
- W2389733515 title "Correlation of COX-2 and VEGF-C expressions with lymph node metastasis in human colon carcinoma" @default.
- W2389733515 hasPublicationYear "2012" @default.
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