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- W2389738105 abstract "OBJECTIVE To analyze the genes of beta-lactamase(BLA),aminoglycosides-modifying enzymes(AMEs),resistant to disinfectants-sulfanilamide(qacE△1-sul1),class 1 integrase(intⅠ1),and the qnr gene associated with plasmid-mediated quinolone resistance in clinical isolate 0524 of Acinetobater baumannii. METHODS The bacterial susceptibility to antimicrobial agents for strain 0524 was determined by Kirby-Bauer method.(Three-dimensional) extract test was used to detect the β-lactamase phenotype of strain 0524.The genes of BLA,qnr,AMEs,qacE△1-sul1,and intⅠ1 were analyzed using PCR and verified DNA sequencing. RESULTS The strain 0524 of A.baumannii was resistant to the third-generation cephalosporins,cefoxitin,ciprofloxacin,and amikacin,susceptible to cefepime,imipenem,and cefoperazone-sulbactam.AmpC β-lactamases were positive.TEM-1,DHA-1,acc(3)-Ⅰ,aac(6′)-Ⅰ,ant(3″)-Ⅰ,qacE△1-sull and intⅠ1 were positive. CONCLUSIONS It has complicated mechanism of drug resistance." @default.
- W2389738105 created "2016-06-24" @default.
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- W2389738105 date "2006-01-01" @default.
- W2389738105 modified "2023-09-25" @default.
- W2389738105 title "DHA-1 Type Cephalosporinase Accompanied with TEM-1 and Class 1 Integron in Clinical Isolates of Acinetobater baumannii" @default.
- W2389738105 hasPublicationYear "2006" @default.
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