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- W2389741344 abstract "Chitosan was modified by sulfation and carboxylmethylation to give sulfated chitosan(SC) and carboxymethyl chitosan(CMC).Each modified polysaccharide was fractionated by ethanol precipitation to give two zwitterionic polysaccharide(ZPS) fractions,sulfated chitosan fraction A (SCA),sulfated chitosan fraction B (SCB),carboxymethyl chitosan fraction A (CMCA),carboxymethyl chitosan fraction B (CMCB).The obtained four polysaccharides were tested on the activity of lymphocytes proliferation in vitro and in vivo.The results showed that they had no effect on the proliferation of lymphocytes in vitro.But the O-carboxymethylated fractions CMCA and CMCB could enhance T lymphocyte proliferation in vivo.These results indicated that the O-carboxymethyl group is the important group to the activity." @default.
- W2389741344 created "2016-06-24" @default.
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- W2389741344 date "2010-01-01" @default.
- W2389741344 modified "2023-09-26" @default.
- W2389741344 title "Preparation of zwitterionic polysaccharides and their effects on lymphocyte proliferation in vitro and in vivo" @default.
- W2389741344 hasPublicationYear "2010" @default.
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