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- W2389742730 abstract "Objective To explore the relationship between YMDD mutation and the markers of HBV in the no antivirus-treated chronic hepatitis B.Methods The contents of HBV-DNA,YMDD mutants were detected by fluorescence quantitative polymerase chain reaction assay(FQ-PCR).The markers of HBV were detected by enzyme-linked immunoadsordent assay(ELISA).Results The rate of YMDD mutation was 13.5% in 89 chronic hepatitis B untreated by anti-virus,of which YIDD accounted for 12.9% and YVDD accounted for 0.6%,respectively.As to HBV markers,YMDD mutation mainly occurred in HBeAg positive patients.HBeAg positive rate was 10.1% and HBeAb positive rate was 3.4%.Conclusions Among chronic hepatitis B without anti-virus treatment,there was a highly YMDD mutation rate.Most mutants were YIDD mutant and occurred in HBeAg positive patients." @default.
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- W2389742730 date "2006-01-01" @default.
- W2389742730 modified "2023-09-25" @default.
- W2389742730 title "Analysis of YMDD Mutation in the no Antivirus-treated Chronic Hepatitis B" @default.
- W2389742730 hasPublicationYear "2006" @default.
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