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- W2389746586 abstract "ObjectiveTo investigate the relationship between expression of Fas/Fas ligan d(FasL), Bcl 2/Bax, ICE and HDV/HBV infection, and their roles in hepatocyte apoptosis in tupaia with HDV/HBV infection Me thodsFas/FasL, Bcl 2/Bax, ICE and apoptosis w ere determined in liver tissues o f tupaia with HDV/HBV infection by immunohistochemistry and in situ e nd labeling techniques Results There were significant correlations bet ween expression of HDAg and Fas/FasL,Bcl 2/Bax,ICE( P 0 05 ) The more the expression of HDAg was, the more were the expression of Fas,FasL,Bax and ICE and the less was expression of Bcl 2 Expression of Fas/FasL,Bcl 2/Bax and ICE were closely correlated to the hepatocyte apoptosis( P 0 05) The more expression of F as, FasL, Bax and ICE were, the more was hepatocyte apoptosis; and the more was expression of Bcl 2, the less was hepatocyte apoptosis ConclusionExpression of Fas/FasL,B ax and ICE may be induced by HDAg in hepatocyte, and Bcl 2 not Fas /FasL,Bcl 2/Bax and ICE may play important roles in hepatocyte apoptosis in HDV infection" @default.
- W2389746586 created "2016-06-24" @default.
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- W2389746586 date "2001-01-01" @default.
- W2389746586 modified "2023-09-25" @default.
- W2389746586 title "Hepatocyte apoptosis on the liver tissues in tupaia with HDV/HBV infection" @default.
- W2389746586 hasPublicationYear "2001" @default.
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