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- W2389758631 abstract "AIM To observe the change of leptin in the controlled Hyperstimulation and to study the correlation between the leptin levels and other reproductive hormones, FSH,LH, PRL, E 2, P and T. METHODS We collected peripheral blood samples in different periods of 21 cycles of the controlled hyperstimulation and the follicular fluid from follicle with diameter14 mm. Normal menstrual cycle was taken as a control group and circulation blood was collected in the period near ovulation. The leptin was detected by means of ELISA. Other reproductive hormones were detected by RIA. RESULTS The blood leptin level of the patients under cycle of the controlled hyperstimulation treatment before their follicular puncture was obviously higher than that when the function of their ovaries was restricted to the greatest degree by using GnRH a to the patients ( P 0.01). The blood leptin level of the patients under cycle of the controlled hyperstimulation treatment before their follicular puncture was higher than that in the normal menstrual cycle ( P 0.05). There was a positive correlation between leptin concentration and peripheral blood ( r =0.947, P 0.05) and a negative correlation between leptin and LH in follicular fluid of the controlled hyperstimulation cycle ( r =-0.604, P 0.05) and a positive correlation between leptin and T ( r = 0.634 , P 0.05). No correlation was found between leptin and FSH, LH, E 2, P except T in the peripheral blood of cycle of the controlled hyperstimulation. Leptin was positively related to T ( r = 0.789 , P 0.05). CONCLUSION Leptin comes from peripheral blood. It turns out that leptin and reproductive hormones affect each other in the body. Leptin takes a role in the regulation of reproductive function." @default.
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- W2389758631 date "2002-01-01" @default.
- W2389758631 modified "2023-09-24" @default.
- W2389758631 title "Correlation between leptin and other reproductive hormones during cycle of controlled hyperstimulation" @default.
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