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- W2389767535 abstract "Aim To explore the effect on oxidative stress of the elderly undergoing TVP surgery of nitroglycerin infusion and the change of plasma NO and MDA.Methods Forty male patients,who were divided randomly into two groups based on whether they had hypertension.Non-hypertension group into group Ⅰ,Ⅱ again,hypertension group into groups Ⅲ,Ⅳ,each group of 10 cases.Group Ⅰ,Ⅲ did not infuse nitroglycerin during operation,group Ⅱ,Ⅳ infuse nitroglycerin instantly by using a target-controlled with 1 μg·kg-1·min-1 from the beginning to the end of surgery.Results Plasma NO levels in group Ⅰ or group Ⅱ were significantly higher than those in group Ⅲ or group Ⅳ before operation(P0.01),at 60,90 min during operation plasma NO in group Ⅰ,Ⅲ were obviously lower than those before operation(P0.05 or P0.01).Conclusion For elderly patients with hypertension their plasma NO levels are lower and plasma MDA levels are higher.Infused nitroglycerin might provide plasma NO for the elderly surgery patients,simultaneously reduces plasma MDA levels." @default.
- W2389767535 created "2016-06-24" @default.
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- W2389767535 date "2010-01-01" @default.
- W2389767535 modified "2023-09-28" @default.
- W2389767535 title "Effect of nitroglycerin infusion on plasma NO,MDA in the elderly undergoing TVP surgery" @default.
- W2389767535 hasPublicationYear "2010" @default.
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