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- W2389776426 abstract "Objective To establish an animal model of mandibular defect distraction osteogenesis of rabbits and lay an experimental foundation for studying distraction osteogenesis.Methods 25 healthy adykt rabbits were divided randomly into 6 groups.5 groups were experimental groups,with 4 rabbits in each.1 group was experimental control group with 5 rabbits in it.Unilateral mandibular osteotomy was performed on 25 rabbits.By operation,a self-made distractor was implanted.After a 6-day latency,the rabbits of experimental groups underwent distraction at the rate of 0.4mm×2/day for 8 days and entered into the consolidation period.4 rabbits were respectively sacrificed at different time points(4 days,8 days after distraction and 2 weeks,4 weeks,6 weeks after consolidation).Experimental control group did not receive the distraction after osteotomy.Every rabbit was respectively sacrificed at corresponding time in experimental groups.The mandibles were harvested to examine the results of bone healing.Results The distractor is able to get both effective distraction and steady fixation.The mandibles of experimental groups were distracted successfully,and new bone tissue had formed in the distraction gaps.Conclusion The animal model of mandibular defect distraction osteogenesis of rabbit established in this study is a suitable one." @default.
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- W2389776426 date "2007-01-01" @default.
- W2389776426 modified "2023-09-26" @default.
- W2389776426 title "Establishment of animal model of mandibular defect distraction osteogenesis in rabbits" @default.
- W2389776426 hasPublicationYear "2007" @default.
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