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- W2389778846 abstract "Objective To evaluate whether dexmedetomidine can be used safely to reduce the incidence of early emergence agitation in children after tonsillectomy.Methods 60 children,5 to 14 years old,undergoing anesthesia for tonsillectomy were randomly divided into 3 groups :control group,the low dexmedetomidine concentration group and the high dexmedetomidine concentration group.Dexmedetomidine was given intravenously at a dose of 0.5μg/kg or 1 μg/kg over a 10-minute period via a computer controlled infusion pump.The HR,SpO 2 and NIBP were recorded in both OR and PACU.Several designated time points were recorded.After patient arrival at the PACU,VAS score,RSS,the occurrence of emergence agitation were recorded every 5 minutes for the first 30 minutes,and every 10 minutes for the next 30 minutes after endotracheal tube was removed.Results There was a significant difference in the incidence of EA between control group and the high concentration group after the removal of endotracheal tube (P 0.05).There was a significant difference in the VAS pain scores and in the RSS between the three groups at the time of extubation,as well as 5 minutes and 10 minutes after extubation (P0.05).Conclusion Dexmedetomidine appears to be safe and effective to reduce the incidence of early emergence agitation in children after tonsillectomy in a dose dependent manner." @default.
- W2389778846 created "2016-06-24" @default.
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- W2389778846 date "2013-01-01" @default.
- W2389778846 modified "2023-09-23" @default.
- W2389778846 title "Clinical evaluation on the effectiveness of dexmedetomidine on emergence agitation after tonsillectomy in children" @default.
- W2389778846 hasPublicationYear "2013" @default.
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