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- W2389789849 abstract "Objective To investigate the expression change and the possible mechanism of matrix metalloproteinase-9(MMP-9)and Platelet-Activating Factor(PAF)in rat brain tissue at the background of lytic cocktail on the early acute cerebral infarction injury.Method 126 adult male SD rats were randomly divided into three groups:control group,model group and sub-hibernation group(giving lytic cocktailⅡintramuscularly after the modeling).The neurological scores of each group were evaluated at 4 hours,12 hours,24 hours after ischemia.Then,the general organic shape of the ischemic rats brain tissue was detected by HE staining,the expression of PAF was detected by immunohistochemical Sp and the expression of MMP-9 was detected by the RT-PCR technical.Result Compared with model group,MMP-9 and PAF content decreased in the sub-hibernation group(P0.05),neurological deficit scores were reduced(P0.05).Conclusion Lytic cocktail has the early cerebral protective effect on acute cerebral infarction injury." @default.
- W2389789849 created "2016-06-24" @default.
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- W2389789849 date "2013-01-01" @default.
- W2389789849 modified "2023-09-26" @default.
- W2389789849 title "Influence of Durg-induced sub-hibemation on acute cerebral infarction injury in rats" @default.
- W2389789849 hasPublicationYear "2013" @default.
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