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- W2389844186 abstract "Objective Plasma cardiac troponin I(cTnI) and B-type natriuretic peptide(BNP) levels were measured in patients with acute dyspnea.The value of cTnI and BNP for diagnosing cardiac dyspnea was assessed.Methods 129 patients with acute dyspnea were enrolled in this study.The diagnosis was cardiac dyspnea in 63 patients and noncardiac dyspnea in 66 patients.All patients underwent cTnI and BNP assay.The relation of logcTnI and logBNP levels with LVEF in cardiac dyspneic patients was assessed.The value of cTnI and BNP for the diagnosis of cardiac dyspnea was appraised.Results The BNP levels among patients in cardiac dyspneic group were significantly higher than those in noncardiac dyspneic group(P0.01).The cTnI levels among patients in cardiac dyspneic group were significantly higher than those in noncardiac dyspneic group(P0.01).In patients with systolic heart failure,the concentration of logBNP had a negative correlation with LVEF(r=-0.739,P0.01).The optimal BNP cut-off value of 112.68 pg/mL for the diagnosis of cardiac dyspnea had a sensitivity of 94%,a specificity of 79%,a positive predictive value of 81% and a negative predictive value of 93%.The area under the ROC curve was 0.941(P0.01).Conclusion Used in conjunction with other clinical information,measurement of B-type natriuretic peptide is valuable for diagnosing cardiac etiologies of dyspnea in patients with acute dyspnea." @default.
- W2389844186 created "2016-06-24" @default.
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- W2389844186 date "2012-01-01" @default.
- W2389844186 modified "2023-09-25" @default.
- W2389844186 title "Utility of cardiac biomarkers in the diagnosis of cardiac etiologies of dyspnea" @default.
- W2389844186 hasPublicationYear "2012" @default.
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