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- W2389884088 abstract "Objective To determine the effect of narrow-band ultraviolet B(NB-UVB) on level of IFN-γ in serum and skin lesions in psoriasis vulgaris(PV) patients.Methods Twenty PV patients were randomized into NB-UVB group(receiving phototherapy,3 times/week,4 weeks) and control(receiving conventional therapy without phototherapy),10 in each.Serum IFN-γlevel was determined by the standard scores of PASI and ELISA,the expression of IFN-γ in psoriasis skin lesions by FQ-PCR.Another 10 healthy subjects receiving medical examination in our hospital in the corresponding time period were enrolled as normal control group.Results PASI score decreased significantly in 2 groups after treatment(P0.05),lower in NB-UVB group(2.6±2.5) than in control group(7.4±1.3).The level of serum IFN-γ decreased significantly in 2 groups after treatment(P0.05),lower in NB-UVB group than in control group(P0.05).Conclusion NB-UVB can regulate serum IFN-γ level and IFN-γmRNA expression of PV and improve imbalance of cytokines,to achieve therapeutic effect." @default.
- W2389884088 created "2016-06-24" @default.
- W2389884088 creator A5020536785 @default.
- W2389884088 date "2009-01-01" @default.
- W2389884088 modified "2023-09-26" @default.
- W2389884088 title "Effect of Narrowband Ultraviolet B on IFN-γ in Serum and Skin Lesions in Psoriasis Patients" @default.
- W2389884088 hasPublicationYear "2009" @default.
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