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- W2389898203 abstract "Osteoclasts(OC) were obtained by a co-culture system with SD rat spleen cells and osteoblasts.In the conversion process,different strengths of calcium,phosphorus and different concentration ratios of calcium to phosphorus were added to the co-culture system,respectively.The formation and activation of OC was detected by morphologic observation,histochemical staining for tartrate-resistant acid phosphatase(TRAP) and detection of lacunar resorption through scanning electron microscopy,respectively.The formation and activation of OC was inhibited by high concentrations of calcium and phosphorus(P0.05).,and the difference between the high concentration group and the control group was very significant.Moreover,the formation and activation was inhibited mostly by the ratio of calcium to phosphorus(2∶1).The results demonstrated that calcium and phosphorus inhibit bone absorbing activity by inhibiting the formation and activation of OC." @default.
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- W2389898203 date "2007-01-01" @default.
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- W2389898203 title "Effects of calcium and phosphorus on the formation and activation of SD rat's osteoclasts cultured in vitro" @default.
- W2389898203 hasPublicationYear "2007" @default.
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