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- W2389899408 abstract "Objective:To compare the efficacy and side effects of Quetiapine and Risperidone in treatment of first-episode schizophrenia.Methods:68 patients met the criteria of CCMD-3 for first-episode schizophrenia were divided randomly to Quetiapine group and Risperidone group.The patients were evaluated with the Positive and Negative Symptom Scale(PANSS),understanding test,digit span test,picture test and the Treatment Emergent Symptom Scale(TESS)before treatment and at the end of 1st,2nd,4th and 8th week.Results:There was no significant difference between Quetiapine group and Risperidone group about therapeutic efficacy and incidence of adverse effects after 8 weeks(P0.05).Incidence of extra-pyramidal symptoms in Quetiapine group were significantly lower than those in Risperidone group(P0.05).Changes of electrocardiogram in Quetiapine group were significantly higher than those in Risperidone group(P0.05).Conclusions:Quetiapine is as effective as Risperidone for treating first-episode schizophrenia with less incidence of extra-pyramidal symptoms and more changes of electrocardiogram as Risperidone." @default.
- W2389899408 created "2016-06-24" @default.
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- W2389899408 date "2008-01-01" @default.
- W2389899408 modified "2023-09-28" @default.
- W2389899408 title "A comparative study between Quetiapine and Risperidone in the treatment of first-episode schizophrenia" @default.
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