Matches in SemOpenAlex for { <https://semopenalex.org/work/W2389938590> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2389938590 abstract "AIM:To observe the hypertrophy effect induced by urot en sinⅡ(UⅡ) on cultured cardiomyocytes and the relation with calcium.MET HODS:The effect of UⅡon cardiac myocyte (MC) hypertrophy was assessed by measurement of cell surface area, protein content and 3H-leucine incorpo ration, the UⅡ-induced changes of Ca 2+ in the MC were observed by means of laser scanning confocal microscope(LSCM). RESULTS: ①UⅡ inc reased MC surface area in a dose dependent manner. After 10 -8and 10 - 7 mol/L UⅡwere added,the cell surface areas were 2046±268 and 3662±259 μm 2, respectively,significantly higher than the surface area of the control( P0.01).②10 -8 and 10 -7 mol/L UⅡincreased 3H-leucine incorporation also in a dose dependent manner. The protein content were 1.7±0 .4 and 1.9±0.3(ng/cell)respectively, and 3H-leucine incorporations wer e 2508±299 and 2898±625 (cpm/ well) respectively.They were all significantly higher than those of the control(P0.01).③A rapid increase of Ca 2+ in MC was observed shortly after 10 -7 mol/L UⅡ was added in cultured M C.CONCLUSION: UⅡcan induce cardiac myocyte hypertrophy and incre ase of calcium,and calcium maybe was the key factor in the hypertrophy effect induced by UⅡ,which could be useful for the prevention of left ventricular hype rtrophy." @default.
- W2389938590 created "2016-06-24" @default.
- W2389938590 creator A5032220395 @default.
- W2389938590 date "2004-01-01" @default.
- W2389938590 modified "2023-09-23" @default.
- W2389938590 title "UrotensinII induced hypertrophy in cultured cardiac myocytes and the relation with calcium" @default.
- W2389938590 hasPublicationYear "2004" @default.
- W2389938590 type Work @default.
- W2389938590 sameAs 2389938590 @default.
- W2389938590 citedByCount "0" @default.
- W2389938590 crossrefType "journal-article" @default.
- W2389938590 hasAuthorship W2389938590A5032220395 @default.
- W2389938590 hasConcept C126322002 @default.
- W2389938590 hasConcept C134018914 @default.
- W2389938590 hasConcept C1491633281 @default.
- W2389938590 hasConcept C167414201 @default.
- W2389938590 hasConcept C185592680 @default.
- W2389938590 hasConcept C207200792 @default.
- W2389938590 hasConcept C3018686881 @default.
- W2389938590 hasConcept C3018791406 @default.
- W2389938590 hasConcept C519063684 @default.
- W2389938590 hasConcept C55493867 @default.
- W2389938590 hasConcept C71924100 @default.
- W2389938590 hasConcept C86803240 @default.
- W2389938590 hasConceptScore W2389938590C126322002 @default.
- W2389938590 hasConceptScore W2389938590C134018914 @default.
- W2389938590 hasConceptScore W2389938590C1491633281 @default.
- W2389938590 hasConceptScore W2389938590C167414201 @default.
- W2389938590 hasConceptScore W2389938590C185592680 @default.
- W2389938590 hasConceptScore W2389938590C207200792 @default.
- W2389938590 hasConceptScore W2389938590C3018686881 @default.
- W2389938590 hasConceptScore W2389938590C3018791406 @default.
- W2389938590 hasConceptScore W2389938590C519063684 @default.
- W2389938590 hasConceptScore W2389938590C55493867 @default.
- W2389938590 hasConceptScore W2389938590C71924100 @default.
- W2389938590 hasConceptScore W2389938590C86803240 @default.
- W2389938590 hasLocation W23899385901 @default.
- W2389938590 hasOpenAccess W2389938590 @default.
- W2389938590 hasPrimaryLocation W23899385901 @default.
- W2389938590 hasRelatedWork W1975538320 @default.
- W2389938590 hasRelatedWork W1996979315 @default.
- W2389938590 hasRelatedWork W2048127661 @default.
- W2389938590 hasRelatedWork W2055703429 @default.
- W2389938590 hasRelatedWork W2061574479 @default.
- W2389938590 hasRelatedWork W2068474466 @default.
- W2389938590 hasRelatedWork W2073891552 @default.
- W2389938590 hasRelatedWork W2095069855 @default.
- W2389938590 hasRelatedWork W2138025010 @default.
- W2389938590 hasRelatedWork W2409829880 @default.
- W2389938590 hasRelatedWork W2409965631 @default.
- W2389938590 hasRelatedWork W2413610352 @default.
- W2389938590 hasRelatedWork W2419554633 @default.
- W2389938590 hasRelatedWork W2420684420 @default.
- W2389938590 hasRelatedWork W2467055029 @default.
- W2389938590 hasRelatedWork W2467638341 @default.
- W2389938590 hasRelatedWork W3141766377 @default.
- W2389938590 hasRelatedWork W3143429441 @default.
- W2389938590 hasRelatedWork W12536447 @default.
- W2389938590 hasRelatedWork W3029812666 @default.
- W2389938590 isParatext "false" @default.
- W2389938590 isRetracted "false" @default.
- W2389938590 magId "2389938590" @default.
- W2389938590 workType "article" @default.