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- W2389968552 abstract "[Objective] To discuss the therapeutic effects of high-frequency electric coagulation under endoscope combined with eradication of Helicobacter pylori (H pylori) on varioliform gastritis (VG). [Methods] 212 cases of VG with H pylori infection were devided into 2 equal groups. The patients in group A were treated with H pylori eradication combined with high-frequency electric coagulation on complete type verruciod focus under endoscope, while those in group B received therapy of eradication of H pylori only. Endoscope and biopsy were performed and the disappearance of verruciform protuberance was observed 4 weeks and 6 months after cessation of treatment respectively. All patients were followed-up. [Results] Three patients (1 in group A, 2 in group B) were withdrawn for the allergic reaction of drugs. And nine patients were dropped out 6 month later (5 in group A, 4 in group B). The eradication rates of H pylori in group A (92.4%) and group B (93.3%) had no significant difference (P 0.05). The disappearance rates of the complete type verrucoid focus in group A were significantly higher than those in group B [4 weeks later: 95.4% (248/260) vs 6.9% (17/245), 6 months later: 87.1% (216/248) vs 19.6% (46/235), all P 0.001]. Followed-up average (41.2±15.5) months in group A and (41.7±15.2) months in group B, incidence of cancer were 0 in group A and 6.0% (6/100) in group B with significant difference between them (P 0.05). [Conclusions] The eradication of H pylori is ineffective for complete type focus in patients with VG. The high-frequency electric coagulation under endoscope combined with eradication of H pylori is effective for complete type verruriform protuberance not only in short-terms but in long-term. It needs more samples to study whether the combination treatment could reduce the incidence of cancer." @default.
- W2389968552 created "2016-06-24" @default.
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- W2389968552 date "2007-01-01" @default.
- W2389968552 modified "2023-09-24" @default.
- W2389968552 title "Therapeutic observation of high-frequency electric coagulation under endoscope combined eradication of helicobacter pylori in patients with varioliform gastritis" @default.
- W2389968552 hasPublicationYear "2007" @default.
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