Matches in SemOpenAlex for { <https://semopenalex.org/work/W2389981807> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2389981807 abstract "Objective To investigate the effect of different treatment on Barrett's esophagus and to explore the mechanism of therapeutic regimen in order to select the most effective one. Methods Fifty-five patients with Barrett's esophagus were diagnosed by endoscopy and biopsy. All patients were randomly divided into four groups: group A (control group), group B (Omeprazole 20 mg, twice a day), group C (Hydrotalcite 1000mg, three times a day), group D (Omeprazole 20 mg, twice a day and Hydrotalcite 1000 mg. three times a day). All patients were treated for three months. Specimens of esophageal tissue were collected and clinical effect was observed with endoscopy before and 1 month, 3 months after treatment. Expression of Cox-2 and Ki-67 in Barrett esophagus were investigated with immunohistochemistry and the differences were analyzed among groups. Results The symptoms of patients in treatment groups were significantly less than group A after treament (P0.05). There was no statistic difference in relieving clinical symptom in group B, C and D (P0.05). Barrett's esophagus was not changed significantly in group B, C, and D with endoscopy. There was a statistic difference in the expression of Cox-2 and Ki-67 in group B, C and D compared to group A(P0.05). The expression of Cox-2 was significantly different in group D compared to group B and C(P0.05). Conclusion Omeprazole or/and Hydrotalcite cann't eradicate Barrett's esophagus, but can relieve clinical symptom and influence the expression of Cox-2 and Ki-67." @default.
- W2389981807 created "2016-06-24" @default.
- W2389981807 creator A5012762693 @default.
- W2389981807 date "2007-01-01" @default.
- W2389981807 modified "2023-09-24" @default.
- W2389981807 title "Changes of the expression of Cox-2 and Ki-67 in Barrett's esophagus before and after treatment" @default.
- W2389981807 hasPublicationYear "2007" @default.
- W2389981807 type Work @default.
- W2389981807 sameAs 2389981807 @default.
- W2389981807 citedByCount "0" @default.
- W2389981807 crossrefType "journal-article" @default.
- W2389981807 hasAuthorship W2389981807A5012762693 @default.
- W2389981807 hasConcept C121608353 @default.
- W2389981807 hasConcept C126322002 @default.
- W2389981807 hasConcept C2775934546 @default.
- W2389981807 hasConcept C2777498785 @default.
- W2389981807 hasConcept C2777785397 @default.
- W2389981807 hasConcept C2777819096 @default.
- W2389981807 hasConcept C2778451229 @default.
- W2389981807 hasConcept C2778589982 @default.
- W2389981807 hasConcept C2781182431 @default.
- W2389981807 hasConcept C2781413609 @default.
- W2389981807 hasConcept C71924100 @default.
- W2389981807 hasConcept C90924648 @default.
- W2389981807 hasConceptScore W2389981807C121608353 @default.
- W2389981807 hasConceptScore W2389981807C126322002 @default.
- W2389981807 hasConceptScore W2389981807C2775934546 @default.
- W2389981807 hasConceptScore W2389981807C2777498785 @default.
- W2389981807 hasConceptScore W2389981807C2777785397 @default.
- W2389981807 hasConceptScore W2389981807C2777819096 @default.
- W2389981807 hasConceptScore W2389981807C2778451229 @default.
- W2389981807 hasConceptScore W2389981807C2778589982 @default.
- W2389981807 hasConceptScore W2389981807C2781182431 @default.
- W2389981807 hasConceptScore W2389981807C2781413609 @default.
- W2389981807 hasConceptScore W2389981807C71924100 @default.
- W2389981807 hasConceptScore W2389981807C90924648 @default.
- W2389981807 hasLocation W23899818071 @default.
- W2389981807 hasOpenAccess W2389981807 @default.
- W2389981807 hasPrimaryLocation W23899818071 @default.
- W2389981807 hasRelatedWork W1552996569 @default.
- W2389981807 hasRelatedWork W2016891497 @default.
- W2389981807 hasRelatedWork W2035793994 @default.
- W2389981807 hasRelatedWork W2077693243 @default.
- W2389981807 hasRelatedWork W2349576973 @default.
- W2389981807 hasRelatedWork W2352569458 @default.
- W2389981807 hasRelatedWork W2354129199 @default.
- W2389981807 hasRelatedWork W2355606060 @default.
- W2389981807 hasRelatedWork W2360030648 @default.
- W2389981807 hasRelatedWork W2367640570 @default.
- W2389981807 hasRelatedWork W2371939956 @default.
- W2389981807 hasRelatedWork W2376892965 @default.
- W2389981807 hasRelatedWork W2377884757 @default.
- W2389981807 hasRelatedWork W2381989487 @default.
- W2389981807 hasRelatedWork W2387647970 @default.
- W2389981807 hasRelatedWork W2388646975 @default.
- W2389981807 hasRelatedWork W2390668326 @default.
- W2389981807 hasRelatedWork W2392883861 @default.
- W2389981807 hasRelatedWork W3028700088 @default.
- W2389981807 hasRelatedWork W3031358613 @default.
- W2389981807 isParatext "false" @default.
- W2389981807 isRetracted "false" @default.
- W2389981807 magId "2389981807" @default.
- W2389981807 workType "article" @default.