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- W2389993957 abstract "Objective To observe the vasoactive intestinal polypeptide(VIP) expression in blood plasma and intestinal mucosa as well as the mast cells count in diarrhea-predominant irritable bowel syndrome(IBS) rats.Methods The SD rats were randomized into normal controlgroup,model control group,Spasmomen treated group and low,medium,high dose Yiji capsule treated group after restrain stress and intracolonic instillation of acetic acid.Indexes for intetinal sensitivity,the content of VIP in plasma and sigmoid mucosa of rats and the MC staining in caecum mucosa of rats were measured by RIA.Results The sensitivity indexes in all groups showed improvement.Yiji capsule significantly lowered the blood plasma and intestinal VIP expressions,as well as the MC count(P0.05).Conclusion The therapeutic effect of Yiji capsule may be realized via reducing expression of VIP in colonic mucosa and MC count." @default.
- W2389993957 created "2016-06-24" @default.
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- W2389993957 date "2011-01-01" @default.
- W2389993957 modified "2023-09-24" @default.
- W2389993957 title "Influences of Yiji Capsule on Vasoactive Intestinal Polypeptide and Mast Cells Expression in Diarrhea-predominant Irritable Bowel Syndrome Rats" @default.
- W2389993957 hasPublicationYear "2011" @default.
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