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- W2390077942 abstract "Objective To observe the function of Tongxinluo and oxiracetam in treating mild cognitive impairment (MCI).Methods An open prospective control study was conducted on 48 cases elder patients with MCI;they were allocated to two groups.The control group(23 cases) was treated with oxiracetam,and the treatment group(25 cases)was combined oxiracetam and Tongxinluo for the therapy.Changes of comprehensive cognitive function,calculation ability of time and space, languages action,attention or execute action were analyzed,and observe the incidence of developing to Alzheimer's disease (AD).Results There were no significant differences of these indexes between the two groups before treatment(P0.05). The comprehensive cognitive function,calculation ability of time and space,languages action,attention or execute action were significantly improved in the treatment group(P0.05),which had no remarkable change in the control group(P0.05), these index in the treatment group was notably higher than the control group(P0.05 ).And it was found in one-year follow-up that the treatment group was lcase(4.0%) but the control group with 3 cases(13.0%) in the incidence of developing to AD,The incidence between the two groups was significant difference(P0.01 ).Conclusion Combined application of Tongxinluo and oxiracetam for treatment can significantly improve the cognitive function of MCI patients,and reduce their incidence of developing to AD." @default.
- W2390077942 created "2016-06-24" @default.
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- W2390077942 date "2011-01-01" @default.
- W2390077942 modified "2023-09-23" @default.
- W2390077942 title "Research on treatment of mild cognitive impairment by Tongxinluo combined with oxiracetam" @default.
- W2390077942 hasPublicationYear "2011" @default.
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