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- W2390085199 abstract "Objective To investigate the effects of calcitonin(CT)intervention on the articular cartilage in rats with osteoarthritis(OA).Methods A total of 60SD rats was equally randomized into surgery group and CT group.The rats in both groups were intervened by cutting off the anterior cruciate ligament and medial meniscus of the right knees,while the left knees were taken as the control samples.Moreover,CT group was subcutaneously injected with CT 15IU/kg every other day on the 2nd day after operation.All the rats were sacrificed on the 7th,14th,21st,28th,42nd and 56th day after surgery,and the gross and histological sections of specimen were observed.Results Compared with surgery group,the synovial membrane hyperplasia,cartilage damage,osteophyte formation and Mankin score were all decreased in CT group.Conclusion CT intervention can effectively improve OA symptom,delay cartilage degeneration and protect articular cartilage in rats with OA." @default.
- W2390085199 created "2016-06-24" @default.
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- W2390085199 date "2014-01-01" @default.
- W2390085199 modified "2023-09-27" @default.
- W2390085199 title "Effects of calcitonin on articular cartilage in rats with osteoarthritis" @default.
- W2390085199 hasPublicationYear "2014" @default.
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