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- W2390090231 abstract "OBJECTIVE To study the clinical distribution and drug resistance characteristics of pathogens from nosocomial infection cases to provide the gist for clinical therapy and control the direction of nosocomial infection.METHODS Gathering samples from impatients in our hospital between Jan 2006 to Dec 2008,we applied the software of WHONET 5.4 for analyzing the cases.RESULTS During the three-year infection surveillance,3311 strains of pathogens were isolated in our hospital,and the clinical isolation rate was 40.1%.The highest infection rate was in Department of Respiratory Disease,and among over 60-year-old sufferers.Among 3311 strains of pathogens from these samples,2132 strains were G-bacilli(64.4%),665 strains were G+ bacteria(20.1%) and 514 strains were fungi(15.5%).The most common species among 3311 pathogen strains were Escherichia coli,Pseudomonas aeruginosa,Klebsiella pneumoniae,Staphylococcus aureus and Candida albicans.The survey of drug resistance strains performed that the detecting rate of MRSA was 26.75%,and the VRSA strains were not detected.Drug resistance results showed that the susceptibility rate of G+ bacteria to vancomycin and minocycline both was the highest.The incidences of E.coli and K.pneumoniae isolates producing extended spectrum beta-lactamases(ESBLs)were 40.1% and 16.4%.The susceptibility rate of G-bacilli to imipenem,meropenem,piperacillin/tazobactam,and cefoperazone/sulbactam was much hiher,the trend of ESBLs prodoing E.coli was increasing every year(P0.05),so as the resistance to the third generation cephalosporin(P0.05).CONCLUSIONS Multiple antibacterial resistance is a important question faced by our hospital,and we should pay attention to promote the rational use of antimicrobial agents and take effective measures to reduce resistance rates of bacteria." @default.
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- W2390090231 date "2010-01-01" @default.
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- W2390090231 title "Pathogens from nosocomial infection cases: clinical distribution characteristics and drug resistance analysis." @default.
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