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- W2390101074 abstract "AMI: To investigate the protective effect of L-carnitine on myocardial damage induced by isoproterenol and its mechanism. METHODS: Rat myocardial ischemia was induced by isoprenaline(ISO) 5 mg/kg injected subcutaneously. Sections of heart were stained with hematoxylin eosin and the degree of myocardial damage was evaluated under the microscope. Rat myocardial mitochondria were isolated, and membrane lipid fluidity (LFU) was determined. RESULTS: The degree of myocardial damage was significantly reduced in the groups treated and pretreated with L-carnitine. Injury of myocardial mitochondra was attenuated in the L-carnitine group. CONCLUSION: L-carnitine may protect the myocardium from damage by isoproterenol and may also have protective effect on LFU of mitochondria damaged by ISO." @default.
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- W2390101074 date "2005-01-01" @default.
- W2390101074 modified "2023-09-25" @default.
- W2390101074 title "Protective effect of L-carnitine on myocardial damage induced by isoproterenol" @default.
- W2390101074 hasPublicationYear "2005" @default.
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