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- W2390102832 abstract "Objective To modify the method of establishing type 2 diabetic model in rats with streptozotocin(STZ) and high-carbon hydrate-fat diet.Methods 40 male SD young rats were selected and the modified key points of methods were as following,1 ﹚ the rats for establishing type 2 diabetic model were 4 weeks old;2 ﹚ to determine the subclinical type 2 diabetes dose of STZ by experiments;3 ﹚ collecting blood from caudal vein,caudal artery and eyeball for the biochemistry test of rats.Results The blood glucose of rats significantly increased(13.7 ± 1.57 mmol/L).The liver,pancreas,brain and kidney of model rats showed pathological changes.The survival time of model rats was longer(over 9 months).Conclusions The study improves the method of establishing type 2 diabetic model." @default.
- W2390102832 created "2016-06-24" @default.
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- W2390102832 date "2011-01-01" @default.
- W2390102832 modified "2023-09-28" @default.
- W2390102832 title "Method Improvement for Model Establishment of Type 2 Diabetes Induced by Streptozotocin and High-carbon Hydrate-fat Diet in Rat" @default.
- W2390102832 hasPublicationYear "2011" @default.
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