Matches in SemOpenAlex for { <https://semopenalex.org/work/W2390115512> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2390115512 abstract "Objective:To prove the existence of apoptosis of neural cells and the therapeutic effect of hyperbaric oxygenation (HBO) after global cerebral ischemiareperfusion injury (CIRI).Methods:Seventytwo SD rats were randomly divided into 4 groups:sham operation group,atmospheric pressure group,hyperbaric air group and HBO group.CIRI was induced by fourvessel occlusion (4VO) for 15 minutes followed by reperfusion for 2 hours.In HBO group rats were subjected to 2 5 ATA (0 25 MPa),95% O 2 concentration for 70 min/d. In hyperbaric air group the rats were treated with 2 5 ATA (0 25 MPa),21% O 2 concentration for 70 min/d. All rats were killed 72 hours after reperfusion.The brain cells were examined with flow cytometry (FCM) and terminal deoxynucleotidyltransferasemediated dUTP nick endlabeling (TUNEL).Results:In atmospheric pressure group and hyperbaric air group,the number of TUNEL stained cells in hippocampal CA1( 103±15 and 96±12 ) was markedly higher than those in sham operation group and HBO group(5±3 and 17±6, all P 0 01).FCM showed obvious subG1 peak.Apoptotic percentages were (1 06±0 48)% and (0 87±0 50)%,respectively,in atmospheric pressure group and hyperbaric air group.These levels were obviously higher than those in sham operation group and HBO group〔(0 34±0 08)%,(0 57±0 37)%,all P 0 05).Conclusions:Apoptosis may take place in the hippocampus CA1 after cerebral ischemiareperfusion.It may provide novel therapeutic approaches for prevention of CIRI.HBO reduces apoptosis in the hippocampus CA1.The preventive mechanism of HBO against CIRI is likely correlated with reduction of apoptosis." @default.
- W2390115512 created "2016-06-24" @default.
- W2390115512 creator A5034568568 @default.
- W2390115512 date "2002-01-01" @default.
- W2390115512 modified "2023-09-23" @default.
- W2390115512 title "Apoptosis of neural cells after global cerebral ischemia-reperfusion injury and the therapeutic effects of hyperbaric oxygenation in rats" @default.
- W2390115512 hasPublicationYear "2002" @default.
- W2390115512 type Work @default.
- W2390115512 sameAs 2390115512 @default.
- W2390115512 citedByCount "0" @default.
- W2390115512 crossrefType "journal-article" @default.
- W2390115512 hasAuthorship W2390115512A5034568568 @default.
- W2390115512 hasConcept C126322002 @default.
- W2390115512 hasConcept C148762608 @default.
- W2390115512 hasConcept C190283241 @default.
- W2390115512 hasConcept C196795494 @default.
- W2390115512 hasConcept C204232928 @default.
- W2390115512 hasConcept C2776268601 @default.
- W2390115512 hasConcept C2780114680 @default.
- W2390115512 hasConcept C2781161787 @default.
- W2390115512 hasConcept C2994405533 @default.
- W2390115512 hasConcept C3017685081 @default.
- W2390115512 hasConcept C42219234 @default.
- W2390115512 hasConcept C541997718 @default.
- W2390115512 hasConcept C55493867 @default.
- W2390115512 hasConcept C71924100 @default.
- W2390115512 hasConcept C86803240 @default.
- W2390115512 hasConceptScore W2390115512C126322002 @default.
- W2390115512 hasConceptScore W2390115512C148762608 @default.
- W2390115512 hasConceptScore W2390115512C190283241 @default.
- W2390115512 hasConceptScore W2390115512C196795494 @default.
- W2390115512 hasConceptScore W2390115512C204232928 @default.
- W2390115512 hasConceptScore W2390115512C2776268601 @default.
- W2390115512 hasConceptScore W2390115512C2780114680 @default.
- W2390115512 hasConceptScore W2390115512C2781161787 @default.
- W2390115512 hasConceptScore W2390115512C2994405533 @default.
- W2390115512 hasConceptScore W2390115512C3017685081 @default.
- W2390115512 hasConceptScore W2390115512C42219234 @default.
- W2390115512 hasConceptScore W2390115512C541997718 @default.
- W2390115512 hasConceptScore W2390115512C55493867 @default.
- W2390115512 hasConceptScore W2390115512C71924100 @default.
- W2390115512 hasConceptScore W2390115512C86803240 @default.
- W2390115512 hasLocation W23901155121 @default.
- W2390115512 hasOpenAccess W2390115512 @default.
- W2390115512 hasPrimaryLocation W23901155121 @default.
- W2390115512 hasRelatedWork W1384930 @default.
- W2390115512 hasRelatedWork W1983363631 @default.
- W2390115512 hasRelatedWork W2014681543 @default.
- W2390115512 hasRelatedWork W2119206829 @default.
- W2390115512 hasRelatedWork W2310416408 @default.
- W2390115512 hasRelatedWork W2338316173 @default.
- W2390115512 hasRelatedWork W2471859317 @default.
- W2390115512 hasRelatedWork W3028974780 @default.
- W2390115512 hasRelatedWork W3029004231 @default.
- W2390115512 hasRelatedWork W3029397431 @default.
- W2390115512 hasRelatedWork W3029930452 @default.
- W2390115512 hasRelatedWork W3030646040 @default.
- W2390115512 hasRelatedWork W3031093915 @default.
- W2390115512 hasRelatedWork W3031392457 @default.
- W2390115512 hasRelatedWork W3032069012 @default.
- W2390115512 hasRelatedWork W3032773717 @default.
- W2390115512 hasRelatedWork W3194940400 @default.
- W2390115512 hasRelatedWork W2418321090 @default.
- W2390115512 hasRelatedWork W2604237400 @default.
- W2390115512 hasRelatedWork W2740144016 @default.
- W2390115512 isParatext "false" @default.
- W2390115512 isRetracted "false" @default.
- W2390115512 magId "2390115512" @default.
- W2390115512 workType "article" @default.