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- W2390147287 abstract "[Objective] To study the acute pulmonary toxicity of ultrafine carbon black. [Methods] Wistar rats were randomly divided into four groups including saline control group, and three level(low, medium and high)of ultrafine carbon black (UFCB)groups. Three test UFCB groups were instilled with suspensions of UFCB via trachea for three days, once every day, and saline control group were instilled with saline only. Pulmonary pathological injury and bronchoalveolar lavage fluid(BALF)of all rats were later examined, including the level of LDH, AKP, ACP, ALB, TP, NOS, MDA. [Results] The amount of LDH, AKP, ACP, ALB, TP, NOS, MDA in exposed groups(medium and high)were all significantly higher than those in control (P0.05). Dose-response relationships were observed in all indices. Pathological changes extended from bronchiole to alveolus and interstitial. [Conclusion] Ultrafine carbon black could induce pulmonary inflammation and oxidative stress injury at both epithelial and interstitial sites." @default.
- W2390147287 created "2016-06-24" @default.
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- W2390147287 date "2007-01-01" @default.
- W2390147287 modified "2023-09-26" @default.
- W2390147287 title "Study on Acute Pulmonary Effects of Rats Induced by Ultrafine Carbon Black" @default.
- W2390147287 hasPublicationYear "2007" @default.
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