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- W2390149315 abstract "A new tadalafil analogue was found, along with nortadalafil, using HPLC-DAD during the inspection of a health product sold without official approval. The analogue was separated using a semi-preparative HPLC system and its structure was determined by a combination of mass spectrometry and NMR spectroscopy. The compound was identified as a tadalafil analogue in which the N-methyl group of tadalafil was replaced with a tadalafil precursor moiety. Nuclear Overhauser effect spectroscopy experiments suggested a cis-relationship between the substituents on a piperidine ring in the tadalafil moiety." @default.
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- W2390149315 date "2016-05-17" @default.
- W2390149315 modified "2023-09-24" @default.
- W2390149315 title "Isolation and structural elucidation of a new tadalafil analogue in health supplements: bisprenortadalafil" @default.
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- W2390149315 doi "https://doi.org/10.1080/19440049.2016.1179134" @default.
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