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- W2390160047 abstract "Objective To establish an HPLC method for content determination of beclomethasone and ethylparaben in Beclometasone and Urea Cream.Methods HPLC analysis was carried out on Diamonsil C18column(250 mm × 4.6 mm,5 μm) and with C2H3N-H2O(30∶ 70) as the mobile phase.The detection wavelength was 240 nm,the flow rate was 1.0 ml·min-1and the column temperature was 45 ℃.Results Beclomethasone showed a good linear relationship in the range of 3.94-23.64 μg·ml-1(r = 0.9999),and ethylparaben in the range of 4.78-28.68 μg·ml-1(r = 1.0000).The recovery and RSD of beclomethasone and ethylparaben in Beclometasone and Urea Cream were 99.7%,0.92%,100.4% and 0.40%,respectively.Conclusion This method is simple,accurate and repeatable,which is suitable for content determination of beclomethasone and ethylparaben in Beclometasone and Urea Cream." @default.
- W2390160047 created "2016-06-24" @default.
- W2390160047 creator A5019320830 @default.
- W2390160047 date "2014-01-01" @default.
- W2390160047 modified "2023-09-23" @default.
- W2390160047 title "Determination of Beclomethasone and Ethylparaben in Beclometasone and Urea Cream by HPLC" @default.
- W2390160047 hasPublicationYear "2014" @default.
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