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- W2390180917 abstract "Objective To investigate the activity of Th1 cells in mice immunized with recombinant MUC1-MBP fusion protein.Methods The levels of IL-2 and IFN secreted by splenocytes and the serum TNF were detected in mice immunized by recombinant MUC1-MBP.Immunohistochemistry technique was used to analyze the infiltration of CD4+ T cells into cancerous tissue of MUC1-MBP immunized mice.Results The levels of IL-2 and IFN secreted by splenocytes and the serum TNF were higher in MUC1-MBP-immunized mice than those in the groups of negative control.MUC1-MBP induced the infiltration of CD4+ T cells into cancerous tissue.Conclusion The recombinant MUC1-MBP fusion protein can activate Th1 cells of mouse." @default.
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- W2390180917 date "2007-01-01" @default.
- W2390180917 modified "2023-09-23" @default.
- W2390180917 title "Recombinant MUC1-MBP fusion protein activates mouse Th1 cells" @default.
- W2390180917 hasPublicationYear "2007" @default.
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