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- W2390195870 abstract "Objective To establish a brain and thorax impact injury animal model with injury having stable degree to fit for the needs of experiment,and study the variation and meaning of plasma IL-6、IL-10 content early after the injury.Methods Self-made animal impact injury minimachine with suitable parameters was used to establish the brain and thorax impact injury animal model.Plasma IL-6、IL-10 content was measured by ELISA.Results Brain and thorax impact injury model was successfully established.Plasma IL-6、IL-10 increased significantly early after injury.They were(511.81±65.68)pg/ml,(103.36±9.45)pg/ml;(322.16±33.08)pg/ml,(79.23±10.26)pg/ml;(138.05±68.75)pg/ml,(49.28±6.21)pg/ml at 6,24,72h after impact injury respectively.Conclusion This animal model with injury of stable degree can be repeated easily and fit for the needs of multi-injury experimental study.The increase of plasma IL-6、IL-10 early after injury may play an important role in the inflammatory reaction and secondary injury after impact injury and relate to the severity of injury significantly." @default.
- W2390195870 created "2016-06-24" @default.
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- W2390195870 date "2005-01-01" @default.
- W2390195870 modified "2023-09-28" @default.
- W2390195870 title "Changes and significance of plasma IL-6、IL-10 content after rat brain and thoracic impact injury" @default.
- W2390195870 hasPublicationYear "2005" @default.
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