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- W2390237338 abstract "Objective To explore the influence of smoking on coagulation function and interleukin-6(IL-6) and high-sensitivity c-reactive protein(hs-CRP) in patients with chronic obstructive pulmonary disease.Methods 90 hospitalized patients with chronic obstructive pulmonary disease in acute exacerbation(AECOPD) were included as the case group,100 healthy persons were selected as control group.The levels of blood coagulation and D dimers and hs-CRP were measured by ELISA.The levels of blood IL-6 were measured by RIA.Results The variation trend of the Fibrinogen and D dimers was the same as that of IL-6 and hs-CRP in patients.Fibrinogen and D dimers levels were significantly higher in case group than that in control group,the indexes above were significantly higher in acute exacerbation period than that of remission,higher in smokers than that of non-smokers in the case group and in control group these were also significantly higher in smokers than non-smokers(P 0.05).Conclusions Smoking is related with the airway inflammation and high condensation state caused by COPD.Smoking is a stable condition,which is important factor affecting COPD.COPD patients should give up smoking and accept anticoagulant therapy as soon as possible." @default.
- W2390237338 created "2016-06-24" @default.
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- W2390237338 date "2013-01-01" @default.
- W2390237338 modified "2023-09-24" @default.
- W2390237338 title "Effects of smoking on coagulation function,interleukin-6( IL-6) and high-sensitivity c-reactive protein( hs-CRP) in patients with chronic obstructive pulmonary disease" @default.
- W2390237338 hasPublicationYear "2013" @default.
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