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- W2390250600 abstract "Objective: To explore the possible anticancer effect of arsenic trioxide (As 2O 3) on oral cancer in vitro.Methods: Tongue squamous cell carcinoma cell Tca8113 and cells isolated from clinical tongue squamous cell carcinoma specimen was used in vitro studies. The anticancer effect of As 2O 3 on oral carcinoma cell cancer was studied by MTT Assay and human tumor colony Assay (HTCA).Results: As 2O 3 obviously inhibited the growth and survial of Tca8113 and Tongue cancer ell. The tumor inhibition rate (TLR) was 86.3% and the tumor colony forming inhibition rat was 91.3% for the Tca8113 with 3umol As 2O 3. The drug sensitity of antitumor drugs was 47.2% with 3umol As 2O 3、36.5% with the MTX、41.3% with the 5 Fu and 58.6% with the PYM for cells isolated from the tongue carcinoma specimen. Conclusion: The As 2O 3 might be one efficient drugs in the treatment of oral squamous cell carcinoma in vitro study." @default.
- W2390250600 created "2016-06-24" @default.
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- W2390250600 date "1999-01-01" @default.
- W2390250600 modified "2023-09-25" @default.
- W2390250600 title "PRELIMINARY STUDY OF ARSENIC TRIOXIDE IN THE TREATMENT OF ORAL SQUAMOUS CELL CARCINOMA" @default.
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